منابع مشابه
Growth hormone therapy in children with chronic renal failure.
Growth is impaired in a chronic renal failure. Anemia, acidosis, reduced intake of calories and protein, decreased synthesis of vitamin D and increased parathyroid hormone levels, hyperphosphatemia, renal osteodystrophy and changes in growth hormone-insulin-like growth factor and the gonadotropin-gonadal axis are implicated in this study. Growth is adversely affected by immunosuppressives and c...
متن کاملImpaired renal growth hormone JAK/STAT5 signaling in chronic kidney disease.
BACKGROUND Treatment with recombinant human growth hormone (GH) is the standard therapy for short stature in children with chronic kidney disease (CKD). However, concerns have been raised on the potential renal fibrogenic effects of GH. There is no information regarding the renal GH receptor (GHR)-JAK-STAT signaling pathway in CKD. METHODS Subtotal nephrectomized (CKD) and pair-fed sham-opera...
متن کاملImpaired glucose tolerance and growth hormone in chronic liver disease.
Of 30 patients with chronic liver disease 16 showed some degree of impairment of glucose tolerance, and 16 patients had lack of suppression of raised fasting growth hormone levels or showed an anomalous rise after oral glucose. No relationship, however, existed between the state of glucose tolerance and the presence of abnormal growth hormone levels. Plasma glucose in those with normal growth h...
متن کاملComparison of Growth Parameters in Two Groups of Children with Chronic Renal Failure Treated with and without Growth Hormone Replacement Therapy
Objective: The aim of the present study was to evaluate the effect of growth hormone on growth parameters such as Z scores for height, weight, and body mass index (BMI), and height velocity in two groups of children with chronic renal failure (CRF) treated with and without growth hormone.Methods: This longitudinal study was conducted on all children aged 6 months to 16 years with a short ...
متن کاملSerum parathyroid hormone levels and renal handling of phosphorus in patients with chronic renal disease.
In eight patients with advanced renal insufficiency (inulin clearance 1.4-9.1 ml/ min), concentrations of serum calcium (S[CaJ) and phosphorus (S[PJ) were maintained normal (S[Ca] > 9.0 mg/100 ml, (S[P] < 3.5 mg/lOO ml) for at least 20 consecutive days with phosphate binding antacids and oral calcium carbonate. The initial serum levels of immunoreactive parathyroid hormone (S-PTH) were elevated...
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ژورنال
عنوان ژورنال: Indian Journal of Endocrinology and Metabolism
سال: 2012
ISSN: 2230-8210
DOI: 10.4103/2230-8210.93736